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Gene Expression Literature Summary
Assay
Age
In situ reporter (knock in)
11.5 DPC

20 matching records from 20 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Pax3  paired box 3   (Synonyms: Pax-3, Splchl2)
Results  Reference
1J:112275 Bajard L, Relaix F, Lagha M, Rocancourt D, Daubas P, Buckingham ME, A novel genetic hierarchy functions during hypaxial myogenesis: Pax3 directly activates Myf5 in muscle progenitor cells in the limb. Genes Dev. 2006 Sep 1;20(17):2450-64
1J:97318 Brown CB, Engleka KA, Wenning J, Min Lu M, Epstein JA, Identification of a hypaxial somite enhancer element regulating Pax3 expression in migrating myoblasts and characterization of hypaxial muscle Cre transgenic mice. Genesis. 2005 Apr;41(4):202-9
1J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99
1J:319471 Daubas P, Buckingham ME, Direct molecular regulation of the myogenic determination gene Myf5 by Pax3, with modulation by Six1/4 factors, is exemplified by the -111 kb-Myf5 enhancer. Dev Biol. 2013 Apr 15;376(2):236-44
1J:159124 Degenhardt KR, Milewski RC, Padmanabhan A, Miller M, Singh MK, Lang D, Engleka KA, Wu M, Li J, Zhou D, Antonucci N, Li L, Epstein JA, Distinct enhancers at the Pax3 locus can function redundantly to regulate neural tube and neural crest expressions. Dev Biol. 2010 Mar 15;339(2):519-27
1J:252092 Gard C, Gonzalez Curto G, Frarma YE, Chollet E, Duval N, Auzie V, Aurade F, Vigier L, Relaix F, Pierani A, Causeret F, Ribes V, Pax3- and Pax7-mediated Dbx1 regulation orchestrates the patterning of intermediate spinal interneurons. Dev Biol. 2017 Dec 1;432(1):24-33
1J:176192 Hayashi S, Rocancourt D, Buckingham M, Relaix F, Lack of In Vivo Functional Compensation Between Pax Family Groups II and III in Rodents. Mol Biol Evol. 2011 Oct;28(10):2787-98
1J:175786 Ho AT, Hayashi S, Brohl D, Aurade F, Rattenbach R, Relaix F, Neural Crest Cell Lineage Restricts Skeletal Muscle Progenitor Cell Differentiation through Neuregulin1-ErbB3 Signaling. Dev Cell. 2011 Aug 16;21(2):273-87
1J:173637 Horner VL, Caspary T, Disrupted dorsal neural tube BMP signaling in the cilia mutant Arl13b hnn stems from abnormal Shh signaling. Dev Biol. 2011 Jul 1;355(1):43-54
1J:156014 Lagha M, Brunelli S, Messina G, Cumano A, Kume T, Relaix F, Buckingham ME, Pax3:Foxc2 reciprocal repression in the somite modulates muscular versus vascular cell fate choice in multipotent progenitors. Dev Cell. 2009 Dec;17(6):892-9
1J:200546 Lagha M, Mayeuf-Louchart A, Chang T, Montarras D, Rocancourt D, Zalc A, Kormish J, Zaret KS, Buckingham ME, Relaix F, Itm2a is a Pax3 target gene, expressed at sites of skeletal muscle formation in vivo. PLoS One. 2013;8(5):e63143
1J:212088 Mayeuf-Louchart A, Lagha M, Danckaert A, Rocancourt D, Relaix F, Vincent SD, Buckingham M, Notch regulation of myogenic versus endothelial fates of cells that migrate from the somite to the limb. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8844-9
1*J:90568 Relaix F, Rocancourt D, Mansouri A, Buckingham M, Divergent functions of murine Pax3 and Pax7 in limb muscle development. Genes Dev. 2004 May 1;18(9):1088-105
1J:99365 Relaix F, Rocancourt D, Mansouri A, Buckingham M, A Pax3/Pax7-dependent population of skeletal muscle progenitor cells. Nature. 2005 Jun 16;435(7044):948-53
1J:197227 Thuault S, Hayashi S, Lagirand-Cantaloube J, Plutoni C, Comunale F, Delattre O, Relaix F, Gauthier-Rouviere C, P-cadherin is a direct PAX3-FOXO1A target involved in alveolar rhabdomyosarcoma aggressiveness. Oncogene. 2013 Apr 11;32(15):1876-87
1J:254172 Vallecillo-Garcia P, Orgeur M, Vom Hofe-Schneider S, Stumm J, Kappert V, Ibrahim DM, Borno ST, Hayashi S, Relaix F, Hildebrandt K, Sengle G, Koch M, Timmermann B, Marazzi G, Sassoon DA, Duprez D, Stricker S, Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development. Nat Commun. 2017 Oct 31;8(1):1218
1J:109476 Veltmaat JM, Relaix F, Le LT, Kratochwil K, Sala FG, van Veelen W, Rice R, Spencer-Dene B, Mailleux AA, Rice DP, Thiery JP, Bellusci S, Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes. Development. 2006 Jun;133(12):2325-35
1J:336860 Wurmser M, Madani R, Chaverot N, Backer S, Borok M, Dos Santos M, Comai G, Tajbakhsh S, Relaix F, Santolini M, Sambasivan R, Jiang R, Maire P, Overlapping functions of SIX homeoproteins during embryonic myogenesis. PLoS Genet. 2023 Jun;19(6):e1010781
1*J:178989 Yvernogeau L, Auda-Boucher G, Fontaine-Perus J, Limb bud colonization by somite-derived angioblasts is a crucial step for myoblast emigration. Development. 2012 Jan;139(2):277-87
1J:243987 Zalc A, Rattenbach R, Aurade F, Cadot B, Relaix F, Pax3 and Pax7 play essential safeguard functions against environmental stress-induced birth defects. Dev Cell. 2015 Apr 06;33(1):56-66

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory